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Schizophrenia Working Group of the Psychiatric Genomics Consortium Biological insights from 108 schizophrenia-associated genetic loci

A proline residue N-terminal to the FSFG motif (P H4 ) contacts the interface between H4 and H5

The standard conversion from rat to human doses uses a factor of approximately 6.2, meaning a rat dose of 10 g/kg translates to roughly 1.6 g/kg in humans