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Experimental evidence shows that dietary Trp supplementation improves motor deficits, enhances tyrosine hydroxylase expression, inhibits NF-B activation in the substantia nigra, and lowers circulating pro-inflammatory cytokines in toxin-induced, animal PD models [167]

Morphological examination of eyes For semithin sections, eyes were fixed in 1.25% paraformaldehyde and 2.5% glutaraldehyde in 0.1 M cacodylate buffer (pH 7.4)

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Researchers believe combining them could target four metabolic pathways, but no formal data confirms its safety or effectiveness