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This outcome would typically require three to four months of recovery, making the acceleration nothing short of astonishing to observers

Although little is known about the mechanism of LDR exposure, many studies reported DNA damages, oxidative stress, and pro-inflammatory responses as major mediating events induced by an LDR exposure

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In summary, our study supports that MeCbl, a widely prescribed drug, is promisingly repurposed to be an effective therapeutic option to GSDME dependent liver failure, which is characterized with high morbidity and high mortality without efficient clinical therapies