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A designer fusion of IL-22 to an antibody (to extend half-life) is in trials for preventing acute graft-versus-host disease after bone marrow transplant, and conceptually could be used for gut protection in big surgeries like aortic aneurysm repair to reduce intestinal permeability and subsequent sepsis

Amini, M

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It is studied in laboratory research for its role in fat oxidation, lipolysis, adipose tissue metabolism, lipogenesis inhibition, and cartilage repair pathway biology without the IGF-1 stimulation, insulin resistance, or receptor-mediated proliferative effects associated with full-length hGH