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While more research is needed, the current evidence supports B12 as a treatment for nerve pain

Footnotes Edited by: Dawei Chen, University of Kiel, Germany Reviewed by: Eveljn Scarian, University of Pavia, Italy Hong Cheng, Yangzhou University, China Author contributions EK: Conceptualization, Data curation, Formal Analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing original draft, Writing review and editing

Recently, the regulation of the glyoxalase I-II system in plants by exogenous application of chemical treatment was investigated in multiple studies [18, 22, 23], and a close connection between the antioxidant and glyoxalase I-II systems during Cd toxicity [24], salt [22] and heat [23] stress was observed

The later targets specific proteins, such as receptors, on cancerous cells or in the tumor environment