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For example, modifications may be made with reference to any allelic variant or species known in the art, such as any of those shown in any of SEQ ID NOS: 393-414 or 547-552, or other known variants in the technique (see, for example, Section D.5), or the zymogens, the active or catalytically active forms thereof

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Akhoon BA, Pandey S, Tiwari S, Pandey R