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Similarly, the percentage of patients deriving clinical benefit from immunotherapy was higher in the low gene score group (93%) compared to the high gene score group (88%) ( Figure 10D )

Second, the type of exercise is crucial: interventions with monotonous content (e.g., simple walking) may lose efficacy over time, whereas programs incorporating progressive cognitive challenges (e.g., Tai Chi or dual-task training) may sustain benefits over extended periods

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