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Patients with TB4 had healing time decrease by as much as a month versus those that did not take TB4 (4)

Estrogens signal through myriad pathways, including genomic mechanisms mediated by two nuclear receptors (ER and ER) that recruit various co-regulatory proteins and induce transcription at estrogen response elements (EREs), in addition to other promoters by tethering to transcription factors (e.g., AP-1 and NF-B)

Most patients received peripheral-blood stem cells (PBSC) (n = 71), while 31 received bone marrow and six patients received a cord blood graft

Gold-nanosphere mitigates osteoporosis through regulating TMAO metabolism in a gut microbiota-dependent manner