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The elucidation of the identity of possible bioactive compounds was carried out using the method of Kim et al

Furthermore, in light of increasing tumor resistance, it may prove more beneficial to use combination therapies or block multiple metabolic pathways simultaneously rather than relying on a single agent [176]

However, in the intervention process of ferroptosis, it was found that the application of GPX4 inhibitors could not completely block the occurrence of ferroptosis [18, 19], and some ferroptosis was also found in the process of tumour intervention

Thus, a different approach should be used to induce a local production of IL-1