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A therapy targeting the underlying cause of lipedema is not available because the exact etiology of the disorder is not clarified yet

, & Eng, C

Vagni S., F

In this study, we used MYCN -amplified HR-NB patient-derived xenografts (PDXs) and PDX-derived organoid models 12,24,25 to investigate multiple ferroptosis-inducing agents with different mechanisms of action