vitamin b12 injections before chemotherapy Risks: 5 Essential Facts Cancer Patients Must Know Vitamin B12 Supplements and Injections

A 12-week randomized trial demonstrated: Average weight loss of 2.6 kg in AOD-9604 group (1 mg/day) versus 0.8 kg in placebo group Preferential reduction in abdominal and visceral fat deposits No adverse effects on carbohydrate metabolism or insulin sensitivity Non-dose-dependent effects, with higher doses (10 mg/day) producing less weight loss than lower doses However, a subsequent 24-week Phase III trial with 502 subjects incorporating intensive diet and exercise showed no statistically significant weight loss compared to placebo, leading to development termination in 2007

Also, keep the container tightly sealed when it is not in use

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10.1016/j.bbrc.2018.04.078 93 MoriV.AmiciA.MazzolaF.Di StefanoM.ConfortiL.MagniG.et al (2014)