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Although serious GI tract ulcerations and bleeding can occur without warning symptoms, patients should be alert for the signs and symptoms of ulcerations and bleeding, and should ask for medical advice when observing any indicative sign or symptoms including epigastric pain, dyspepsia, melena, and hematemesis

They take 30 to 60 minutes to start working but provide 6 to 12 hours of relief

It can take at least 2-3 months before you see the early signs of improvement