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As a result, the production of immunosuppressive adenosine in cancer cells was reduced, ultimately preventing macrophages from acquiring an M2 immunosuppressive phenotype

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2.3 Measurement of urine GPX4 by feline commercial GPX4 ELISA kit Urine GPX4 levels in the cats were measured using a species-specific commercial ELISA kit (MBS093863, MyBioSource, USA) by following the manufacturers instructions