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It works by blocking a potentially dangerous enzyme called protein disulfide isomerase (PDI) that is rapidly excreted from both endothelial cells and platelets when a clot forms in an artery or vein

J Med Chem 65:876884 Long T, Yang N, Zhou M, Chen D, Li Y, Li J, Tang Y, Liu Z, Li Z et al (2019) Clinical application of 18F-AlF-NOTA-octreotide PET/CT in combination with 18F-FDG PET/CT for imaging neuroendocrine neoplasms

Many patients combine it with hormone replacement therapy for comprehensive hormonal optimization, medical weight loss programs for multi-modal fat reduction, body contouring treatments as body composition improves, and other peptide therapies based on individual goals

Kuchenbauer F, Kern W, Schoch C, Kohlmann A, Hiddemann W, Haferlach T: Detailed analysis of FLT3 expression levels in acute myeloid leukemia