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doi: 10.1007/s40263-015-0272-9 Summary Keywords polycystic ovary syndrome, nutrients, vitamins, minerals, bioactive compounds, metabolism Citation Zhang Y, Shi B, Tian Y, Xu S and Chang H (2026) Nutrients and bioactive compounds in polycystic ovary syndrome: updated insights into effects and underlying mechanisms

Interestingly, a recent study showed that despite the low plasma concentration of polyphenols, polyphenols were transported to the arterial intima at pH 7.4 in the form of bound lipoproteins, and polyphenol levels were significantly elevated in endothelial cells and macrophages (148)

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However, while current findings are encouraging, more rigorous clinical trials are essential to confirm their efficacy, determine optimal dosages, and assess long-term safety profiles