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Weekly ratings were performed using Aberrant Behavior and Symptom Checklist (ABC) 122 with clinician ratings consisting of the Global Assessment Scale, 123 Comprehensive Psychiatric Rating Scale (CPRS), 124 and Clinical Global Improvement, 125 which were assessed at the beginning and then weekly up to the end of the treatment period

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From a prospective viewpoint, the exploration of novel therapies that are both effective and less toxic to normal cells represents a promising frontier in treatment development