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Therefore, high-resolution sub-proteomics, coupled with bioinformatics, were utilized to further expand our knowledge, and understanding of the GST soluble superfamily within this equine helminth

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The expression of IDO was inhibited, the metabolic pathway of Trp was blocked, the formation of Kyn was decreased, the ability of cell death mediated by kyn through reactive oxygen species (ROS) pathway in natural killer (NK) cells decreased (64), vascular tolerance decreased, and promoted the occurrence and development of inflammation and AS (65, 66)