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It further explores the potential of natural metabolic modulators in improving the tumor immune microenvironment and enhancing immunotherapy sensitivity

Further, inhibition of TRPM7 activity attenuates RA articular cartilage destruction and chondrocyte ferroptosis by suppressing the PKC-NOX4 axis (129)

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Furthermore, BHB treatment suppresses oxidative stress in cardiomyocytes and prevents ischemia/reperfusion injury in the mouse heart by reducing ROS production, attenuating mitochondrial swelling, and partially restoring mitochondrial membrane potential (75)