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Similarly, vitamin B12 levels above 900 pg/mL, especially without supplementation, may indicate some serious health complications, including diabetes, leukemia, or liver and kidney disease

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Research models often examine NNMT inhibition in the context of substrate recycling, signaling efficiency, and cellular stress response mechanisms

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The authors thank Irene Orera from the Proteomics Facility of the Centro de Investigacin Biomdica de Aragn for the MRM-MS analysis

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