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J Neurosci Res 66:9981002 Sharma R, Ansari GAS, Awasthi YC (2007) Physiological substrates of glutathione S-transferases

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43 It promotes ethanol oxidation by degrading H 2 O 2 in peroxisomes, but this pathway is not critical in hepatic ethanol metabolism

Future research must focus on promoting the translation of microbiome research from association studies to clinical applications through multi-omics integration and prospective clinical trials, ultimately achieving precise prevention and treatment of liver diseases based on gutliver axis regulation