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Herein, we demonstrate that the disruption of the intestinal barrier function occurs before the onset of the inflammatory phase of autoimmune murine and human arthritis identifying it as checkpoint for the transition from autoimmunity to inflammation

We refer readers to section III.G.4.b.(2)(a) of this final rule for discussion regarding the separate but related proposal to require Shared Savings Program ACOs to report and be scored on the APP Plus quality measure set beginning in the CY 2025 performance period

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