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Key mitochondrial and antioxidant molecules such as Cytochrome c, UCH-L1, and thioredoxin domain-containing protein 12 were significantly downregulated

Thus, Fukuda's criteria consider that the fatigue should not be caused by any conditions that may be identified by specific tests or diagnoses [16]

Whether IT-CHB patient needs treatment requires both individualized and comprehensive assessment implicating multiple factors, such as patient age, willingness to receive treatment, risk of disease progression, virus genotype (Yang et al., 2008

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