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Considering that glutathione is involved in the elimination of harmful substances such as: alcohol, drugs, solvents, pesticides, heavy metals, and many other toxic xenobiotic products that induce a state of cellular stress [71], it is evident that glutathione homeostasis becomes more relevant, because cells require an antioxidant agent that either prevents or reduces this stress, whether by trapping, metabolizing or turning them into less toxic agents [71,101]

Clin Neuropharmacol 36:103106 Remington R, Lortie JJ, Hoffmann H, Page R, Morrell C, Shea TB (2015) A nutritional formulation for cognitive performance in mild cognitive impairment: a placebo-controlled trial with an open-label extension

Indeed, the effect of glycine has always been reported as positive

In liver tissue from Gclc KO mice, we observed an accumulation of glutamate but no difference in cysteine and glycine levels (Fig