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Recombinant Klotho can enhance cholesterol efflux by inhibiting the Wnt/-catenin signaling pathway, thereby reducing lipid accumulation in foam cells

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Free Radic Biol Med 111: 262269, 2017

Other compounds, such as Cardarine GW, have shown promise for treating certain conditions, but have also been found to have potential risks, such as carcinogenic effects, which highlights the need for careful evaluation and testing of new therapies 7m10s