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TB-500 (~5,000 Da) is a Thymosin Beta-4 fragment that regulates actin dynamics and is studied for cardiac, muscle, and dermal repair

Through effectively attenuating the redox-active Fe 2+ accumulation, decreasing the ferroptotic changes, enhancing the Nrf2-mediated anti-oxidative enzymes expression, reducing the production of key inflammatory factors, and suppressing the caspase 3-dependent apoptotic signaling, ALA remarkably protect the liver function and prevent CSD-induced metabolic deficiency (Figure 7)

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