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most were mild to moderate in severity

Methylene Blue , acts as a nootropic, to enhance mitochondrial function leading to a variety of benefits such as increased energy levels, improved physical health, and enhanced cognitive function

Animal studies have found that thymoquinone may help treat burns , excisions , and other types of wounds due to its anti-inflammatory , antioxidant , and antibacterial effects

Size, surface charge, and flexibility are important determinants for cellular internalization of NPs, with lipid-based NPs being more readily internalized than rigid silica or metal-based NPs ( The complexity of the physiological and pathophysiological barriers encountered during the systemic delivery of NPs to the brain complicates the development of successful NP-based therapeutics ( The review intends to give a broad and impartial presentation of the present status of nanoparticle-mediated drug delivery approaches for CNS disorders