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Many studies suggest that small, polar molecules may be able to bypass the bloodbrain barrier with nasal delivery, as the interface between the nasal cavity and brain is considered a potential point of vulnerability in the bloodbrain barrier

Another type of post-translational modification is methylation by arginine methyltransferases (PRMTs), in which arginine can be methylated to either monomethylated arginine or dimethylated arginine

A., Abd Hamid, Z., Budin, S

Among different chemotherapy regimens, only those patients treated with taxane (including steroid premedication) in combination with pembrolizumab show improved OS