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This is because cartilage lacks its own blood supply, relying instead on diffusion from surrounding synovial fluid for nutrient delivery

Hou, X., Rooklin, D., Fang, H

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"Comparative Bioavailability and Utilization of Particular Forms of B12 Supplements With Potential to Mitigate B12-related Genetic Polymorphisms", Integrative Medicine: A Clinician's Journal (Encinitas)