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However, the clinical utility of current antifungal therapies is hindered by challenges such as the emergence of drug resistance, limited antifungal spectra, and adverse side effects

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There may be fillers, preservatives, or artificial flavours that spike sensitivity in some individuals and cause: Hives Facial or throat swelling Difficult breathing Sleep and Energy Disturbances An overdose of glutathione or a rapid detoxification process may trigger over-stimulation, which disrupts sleep patterns

Beyond its energy role, NAD+ is the essential substrate of sirtuins (SIRT1-SIRT7), deacetylases that regulate mitochondrial biogenesis, DNA repair, and resistance to cellular stress (Imai & Guarente, Trends Cell Biol 2014)