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Unlike other metals like iron, the mechanisms of copper-induced cell death are not well understood

Nevertheless, when a person whose intestinal barrier has been compromised by trauma, acute inflammatory conditions such as pancreatitis, burns, or surgery, increased endotoxin concentrations are present in the circulation [42, 56, 57]

Diabetes 49(11):17511760

Transfection of GES-1 cells with miRNA-143, miRNA-152, and miRNA-181 mimics significantly decreased mature miRNA expression accompanied by xCT mRNA, and protein expression was significantly suppressed (Figures 4A,B)