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Geriatric Use In elderly patients, it is recommended that the dosage be limited to the smallest effective amount to preclude the development of ataxia or oversedation (2 mg to 2.5 mg once or twice daily, initially to be increased gradually as needed and tolerated)

Endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation

Zinc is a key component of antioxidant enzymes (e.g., superoxide dismutase)

When we used simultaneous TPEF imaging, we observed that the level of autofluorescent granules is lower in daf-2 mutants, higher in rict-1 mutants, and similar in sgk-1 mutants when compared with wild type worms ( Figure 4B )