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Chen et al indicated that rufinamide can improve cognitive function and increase neurogenesis in the hippocampus of the aged gerbil by increasing the IGF-1, IGF-1R and p-CREB expressions[63]

10.1007/s10528-021-10176-2 113 LuT.ZhangZ.PanX.ZhangJ.WangX.WangM.et al (2022b)

Development of clinically relevant orthotopic xenograft mouse model of metastatic lung cancer and glioblastoma through surgical tumor tissues injection with trocar