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In support of this, shGDH1 cells exhibited reduced expression of mitochondrial electron transport chain (ETC) subunits and lower respiratory capacity, which could be greatly recovered by exogenous -KG (Supplementary Fig

Hughes L, Malone C, Chumsri S, Burger AM, McDonnell S

Rev-erb, reverse erythroblastosis virus

The release and excessive accumulation of collagen fibers caused by overactivated fibroblasts, which are marked with fibroblast activation protein (FAP), lead to pathological changes in the extracellular matrix (ECM) and persistent inflammation, resulting in a vicious cycle of cellular activity and extracellular fibrosis 3,4,5,6,7