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Dose-response relationships appear to be tissue-specific, with adipose tissue showing high sensitivity while other tissues may require higher concentrations for detectable effects

10.1038/leu.2014.185 Summary Keywords CD38, antibody, daratumumab, isatuximab, MOR202, TAK-079, resistance, mode of action Citation van de Donk NWCJ and Usmani SZ (2018) CD38 Antibodies in Multiple Myeloma: Mechanisms of Action and Modes of Resistance

106,107 Despite these promising findings, not all studies have noted efficacy, and more research is needed to identify the optimal intensity and duration of laser therapy

Some symptoms may not show up for a few years until the deficiency worsens and affects other parts of your body