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Description

Polycythemia vera cure remains elusive, as current treatments manage rather than eliminate the disorder, but proper care allows most patients to maintain a good quality of life.

Figures Abstract Background Although reduced glutathione (rGSH) is decreased in obese mice and humans, block of GSH synthesis by buthionine sulfoximine (BSO) results in a lean, insulin-sensitive phenotype

Combinatorial Chemistry & High Throughput Screening

Single agent, canfosfamide (C, TLK286) vs pegylated liposomal doxorubicin (D) or topotecan (T) in 3rd-line treatment of platinum (P) refractory or resistant ovarian cancer (OC): phase 3 study results [Abstract]