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Faubert B, Solmonson A, DeBerardinis RJ

This reduction was associated with downregulated NFB expression and partial suppression of MAPK and AP-1 signaling, elucidating that GAC1 may have potential for treating TNF- mediated inflammation [110]

Astrocytes sense extracellular changes through receptors such as pattern recognition receptors and cytokine receptors, detecting pathogens, A aggregates or inflammatory mediators 4,41