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Microneedling creates transient microchannels in the scalp that bypass the stratum corneum and allow topical actives to reach the follicular unit at depths that surface application cannot achieve

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A Gatan K3 direct electron camera operating in correlated double sampling (CDS) mode equipped post a Gatan Quantum energy filter (Gatan, Pleasanton, CA, USA) was to record movies with a total dose of ~60 e per 2