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In graft-versus-host disease (GVHD) models, inflammation-induced loss of microbial FXR antagonists or pharmacological FXR agonism exacerbated disease

Testicular biopsy score countA method for registration of spermatogenesis in human testes: Normal values and results in 335 hypogonadal males

Furthermore, Sirt3, the principal mitochondrial sirtuin, enzymatically removes acetyl groups from metabolic enzymes via lysine deacetylation

Perhaps most frustrating is post-exertional malaise (PEM), a hallmark symptom where even minor physical or cognitive exertion triggers a severe, delayed crash in baseline functioning