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Supplementary Figure 1a-f ), which were enriched in multiple metabolic processes, among which amino acid metabolisms (e.g., glutamate metabolism, glycine and serine metabolism, and cysteine and methionine metabolism) being the most significantly downregulated pathways upon LDHB KD ( Figure 1b )

The CONVINCE randomized trial found positive effects on quality of life for patients with chronic kidney disease treated with hemodiafiltration