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2 Materials and methods 2.1 Plant raw material Curcuma longa rhizomes were obtained from agroecological crops located in Valle del Cauca, Colombia (latitude = 3 4328 N, longitude = 76 1602 W)

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Semax 5mg Vial Best for: General cognitive support, testing tolerance, or short 4-week cycles Reconstitution: 3.0 mL bacteriostatic water ~1.67 mg/mL concentration Dosing at 1.67 mg/mL: 1 unit = 0.01 mL 16.7 mcg 300 mcg dose: 18 units (0.18 mL) 500 mcg dose: 30 units (0.30 mL) Vials needed for 4-week cycle @ 0.5 mg/day: 3 vials Semax 10mg Vial Best for: Extended protocols, cost-effective bulk research, or higher dose regimens Reconstitution: 3.0 mL bacteriostatic water ~3.33 mg/mL concentration Dosing at 3.33 mg/mL: 1 unit = 0.01 mL 33.3 mcg 300 mcg dose: 9 units (0.09 mL) 500 mcg dose: 15 units (0.15 mL) Vials needed for 8-week cycle @ 0.5-0.8 mg/day: 4 vials For 10unit administrations, consider 30 or 50unit insulin syringes for improved readability