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Increasing preclinical studies have confirmed the antitumor effects of nanomaterials in GBM ( Table 1 ) ( Figure 5 )

The economics of pharmaceutical development do create real evidence gaps for unpatentable molecules, and patients pay the cost of that asymmetry

PLoS One 11:e0141738

In addition to the adverse reactions listed above which have been observed in patients treated with ceftriaxone, the following adverse reactions and altered laboratory test results have been reported for cephalosporin class antibiotics: Allergic reactions, drug fever, serum sickness-like reaction, renal dysfunction, toxic nephropathy, reversible hyperactivity, hypertonia, hepatic dysfunction including cholestasis, aplastic anemia, hemorrhage, and superinfection