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Part of age discrimination in employment and part of the answer to it involve this relationship between work and function: for it wrong to think so much in terms of a person's right or desire to keep on indefinitely at the kind of thing he has always done

Sigalos, John T, and Alexander W Pastuszak

Along these lines it is interesting that elevated expression of mammalian 14-3-3 can promote alpha synuclein extrusion 63 , akin to our finding that 14-3-3 protein FTT-2 is required for efficient exophergenesis and can drive enhanced exopher production when over-expressed in C

In all experiments, age-matched mice were used (unless otherwise stated), WT littermates served as controls, and treatment was randomly assigned to control for cage effect