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Stimulation of de novo glutathione synthesis by NFT concentrations in this range was observed in HepG2 cells, PHHs, or human neuronal cells, but not to the same extent in other cell types such as human iPSC-derived astrocytes

However, in contrast to the Dmrta2 full-length protein, cotransfection of Zfp423 with this Dmrta2 deletion mutant did not further decrease luciferase activity (Fig