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Pyroptosis activation is highly dependent on direct stimulation of immune cells by pathogen-associated molecular patterns, and its core pathological effect is the massive release of potent pro-inflammatory cytokines such as IL-1 and IL-18

4 Discussion 4.1 Summary of evidence This systematic review and meta-analysis indicate that the active components of Schisandra chinensis exhibit significant protective effects against liver injury in animal models

Logistic regression was used to identify singular CpG sites containing hypermethylation (positive meth.diff values) or hypomethylation (negative meth.diff values)