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You may be at higher risk if you: Follow a vegan or vegetarian diet Eat very little meat, fish, eggs, or dairy Are over the age of 50 Have digestive conditions affecting absorption Take certain medications, such as metformin or acid-reducing medicines Have had certain stomach or bowel surgery Have pernicious anaemia or absorption problems People in higher-risk groups may benefit from advice, testing, or treatment depending on their symptoms and medical history

Rong, P., et al

The peptide appears to promote mucosal healing through enhancement of epithelial cell proliferation and migration, restoration of tight junction integrity, and modulation of inflammatory responses within the gastrointestinal tract

The second co-stimulatory signal arises from the engagement of B7.1 (CD80) and B7.2 (CD86) molecules on APCsincluding activated macrophages, dendritic cells, and B cellswith CD28 on T cells