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Post-Exertional Malaise (PEM): While not a cure for PEM, improving mitochondrial efficiency and reducing systemic oxidative stress can help raise a patient's energy envelope, making them slightly more resilient to the metabolic fallout of physical or cognitive exertion

A study among female athletes concluded that choline supplementation was responsible for rapid reduction in body mass without noticeable side effects

From a biochemical standpoint, we're looking for favorable changes in those NAD+ levels and corresponding improvements in markers like fasting glucose and insulin sensitivity

Linton MF, Gish R, Hubl ST, Butler E, Esquivel C, Bry WI, et al