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These observations correlate with those reported by Barrat et al., showing that tamoxifen-derived metabolites (i.e., 4-hydroxy-tamoxifen and endoxifen) also promote oligodendrogenesis in an estrogen receptor-dependent manner, including non-classical ERs (Table 1)

In the brain, MAO-B converts it into a neurotoxin, MPP+, which can cause cell death in dopamine-producing neurons in the substantia nigra

siRNA-mediated knockdown of Nrf2 in BMDMs BMDMs were seeded in a 6-well plate after 6 days of differentiation

These diseases include COPD, asthma, interstitial lung disease, pulmonary sarcoidosis, and pneumoconiosis, such as silicosis and asbestosis (Vilcins et al