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Recent studies have revealed that MERCs play a role in the regulation of cell division, and HMOX2 has been identified as an iron source for cell proliferation 22,46

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From a transfusion standpoint, these discrepancies are notably significant since similar biological processes may yield divergent functional consequences dependent upon the underlying circumstances

For instance, researchers have experimented with CAR-T cells overexpressing PGC-1 (the transcriptional coactivator that drives mitochondrial biogenesis)