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They mark the first rigorous indication that the link between acetyl-L-carnitine levels and depression may apply to people, too

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As a key transcription factor, NRF2 regulates antioxidant and detoxifying enzymes, bolstering the cells ability to resist oxidative stress, toxins, and other harmful stimuli, which can improve disease progression and prognosis [154, 155]

Although GPx4-regulated lipid peroxidation was obviously involved in the regulation of ferroptosis in CS-exposed mouse models, no significant difference of NCOA4 and ferritin expression levels was demonstrated based on the alterations of GPx4 status (Supplementary Fig