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General Principles of Pharmacology: Drug Metabolism Metabolism of acetaminophen in humans. The three pathways, (a) Download Scientific Diagram does lidocaine use glutathione or glucuronidation Medicinal chemistry on metabolism(Phase I & Phase II Reactions) Chronic alcoholism lowers the Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial
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